The defense takes place

Thuesday, December 7th, 2023. Time: 14:00 am
At the department of Clinical Medicine
Place: in room 12.01.004
Selma Lagerløfs Vej 249, Aalborg University

After the defense there will be held a reception. All are welcome.

 

Supervisors

Niels Holmark Andersen, MD, PhD, DMsSC
Department of Cardiology, Aalborg University Hospital

Professor Peter Søgaard, MD, DMSc
Department of Cardiology, Aalborg University Hospital

Kristian Hay Kragholm, MD, PhD
Department of Cardiology, Aalborg University Hospital

Assessment Committee

Clinical associated professor Jon Waarst Gregersen, MD, PhD (Chair). Aalborg University

Professor Thomas Gudbjartsson; MD, PhD. University of Iceland

Associated Professor Jacob Budtz-Lilly, MD, PhD. Aarhus University

 

About the PhD thesis

Through years, large, international referral centre-derived registries  have provided valuable and updated information regarding aortic dissection: patient characteristics, presenting symptoms, diagnostics, management, complications and survival. However, the centre-derived design implies selection bias, thus only patients who reach these centres alive are captured in these registries.

The overall aim of this thesis was to assess characteristics, shortterm outcomes, and long-term outcomes in patients presenting with acute aortic dissection in a nationwide population-based setting providing a more comprehensive insight into all patients with acute aortic dissection. The general conception that type A dissection was a widow maker and type B dissections could be handled conservatively was not necessarily reflected in the long-term survival.

Data on long-term outcomes beyond survival are sparse. However, patients with aortic dissection may suffer from complications such as hypoxic brain injury, stroke, or spinal cord -, limb - or mesenteric ischemia as well as renal failure. These factors may have detrimental effects on the patient’s quality of life and ability to manage without assisted living or nursing home care. Therefore, the thesis aimed to assess the need for home care or nursing home admission in patients who survived an acute aortic dissection and to assess factors related to these needs.

Aortic dilataion is an established risk factor to aortic dissection, and a final aim of the thesis was to determine the relationship between aortic root size and hypertension, age, lifestyle, and cardiovascular risk factors in large adult population-based cohort from The Copenhagen City Heart Study, since data so far have been heterogenous.

 

Contact information

You can contact Maria Weinkouff Pedersen if you have any questions about the defense by clicking here on her e-mail.

Maria Weinkouff Pedersen
E-mail: mwp@rn.dk
Aalborg Universityhospital
Department of Cardiology
9000 Aalborg