PhD defense by Muhammad Samran Navid

The Department of Clinical Medicine, Aalborg University and Aalborg University Hospital are pleased to invite to PhD defense by Muhammad Samran Navid, who will defend the thesis entitled: Effects of Chiropractic Spinal Manipulation on Brain Activity


08.09.2020 kl. 14.00 - 17.00


The PhD defense will take place

Tuesday the 8th of September, 2020 at 2 pm

Because of COVID-19, the PhD defense will be held online.
For registration please write an e-mail to:


Professor Asbjørn Mohr Drewes, MD, DMSc, PhD
Aalborg University Hospital
Aalborg University

Heidi Haavik, BSc (Chiropractic), PhD
New Zealand College of Chiropractic
New Zealand

Imran Khan Niazi, MSc, PhD
New Zealand College of Chiropractic
New Zealand

Dina Lelic, MSc, PhD
Aalborg University Hospital

Assessment Committee

Associate Professor Salome Kristensen, MD, PhD (chair)
Aalborg University

Associate Clinical Professor Dean L. Smith, DC, PhD, ICCSP
Miami University

Senior Lecturer Amit N. Pujari, BE, MSc, PhD, CEng, FHEA, FRSA
University of Hertfordshire


About the PhD thesis

Over the past decade, a lot of research has evaluated the neurophysiological effects of spinal manipulation. It has been proposed that spinal manipulation alters cortical excitability or neural plasticity. However, most of the studies have been performed in one type of patient population. Therefore, for a better understanding of the neural mechanisms altered by spinal manipulation, the research has to be extended in other patient populations.


The objective of this PhD thesis was to investigate the effects of spinal manipulation on the neural processing of pain, and cortical excitability of the damaged brain after stroke.


The PhD thesis is based on four studies. Study I was conducted on healthy persons, and assessed the effects of preprocessing on somatosensory evoked potentials (SEPs). Study II was based on subclinical pain patients, and focused on evaluating the neurophysiological effects and corresponding brain sources to pain following the spinal manipulation. Studies III and IV evaluated the effects of spinal manipulation on the neurophysiology of chronic stroke survivors.


The findings of the thesis suggest that care should be taken in using the SEP preprocessing parameters and that spinal manipulation extends beyond a local effect in muscles, joints, and ligaments. The manipulation impacts the cortical processing of pain, and have an apparent neuroplastic effect in patients surviving a stroke. The results will be presented in detail at the PhD defense.


Department of Clinical Medicine


Online via Skype for Business or Zoom

Tilmelding inden

07.09.2020 kl. 14.00

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