AAU ALUMNI

PhD defense by Maria Buhl Borgstrøm

The Department of Clinical Medicine, Aalborg University and Aalborg University Hospital are pleased to invite to PhD defense by RN, cand. scient. san, Maria Buhl Borgstrøm, who will defend the thesis entitled: The competent blastocyst - Association to the parents age and the child at birth

Tidspunkt

16.12.2021 kl. 14.00 - 17.00

Beskrivelse

The PhD defense will take place

Thursday 16 December, 2021 at 14.00
in Konferencesalen, room 1.001 in building A,
at Aalborg University in Copenhagen, A.C. Meyers Vænge 15

And online at https://aaudk.zoom.us/j/64538643516

After the defense there will be held a reception. All are welcome.

 

Supervisors

Professor Ulrik Schiøler Kesmodel, Fertility Unit, Aalborg University Hospital,
Department of Clinical Medicine, Aalborg University

IVF-laboratory director, Marie Louise Grøndahl, Fertility Clinic,
Herlev and Gentofte University Hospital

Associate professor, Anne Kjærgaard Danielsen, Department of Gastroenterology, Herlev and Gentofte University Hospital, Department of Clinical Medicine, Copenhagen University

Professor, Thordis Thomsen, Department of Anaesthesiology, Herlev and Gentofte University Hospital, Department of Clinical Medicine, Copenhagen University

Professor, Jakob Ingerslev, Fertility Unit, Aalborg University Hospital

Professor, Sjurdur Frodi Olsen, Department of Epidemiological Research,
Statens Serum Institute

 

Assessment Committee

Professor Søren Hagstrøm, Aalborg University (chairman)

Associate professor, Ellen M. Mikkelsen, Department of Clinical
Epidemiology, Aarhus University

Professor Thomas Ebner, Kepler Universitats Klinikum GmbH, Med Campus IV, Linz, Austria

 

About the PhD thesis

This PhD thesis was performed in a collaboration with Aalborg University, Herlev and Gentofte Hospital and 8 public and 8 private fertility clinics in Denmark.

In a cohort of Single Embryo Transfer (SET) blastocysts which was followed-up until pregnancy and live birth the associations between female and male age respectively, and quality parameters of the competent blastocyst and hCG were investigated (study I and II). Further, the associations between quality parameters of the competent blastocyst and obstetric outcomes (preterm birth, birth weight, length at birth and the sex of the child) were investigated (study III).

Study I and II showed a modest association between age (female and male) and the quality parameters of the competent blastocyst. Further, that the youngest females had the lowest level of initial hCG-rise, and the initial hCG-rise in females having a male partner older than 30 years was reduced.

Study III showed an association between the quality parameters of the competent blastocyst and the sex of the child, but no associations with other obstetric outcomes (i.e. preterm birth, birth weight and length at birth).

The findings from the studies have revealed that neither female nor male age have a high impact on the quality parameters of the competent blastocyst. Further, that the youngest females had the lowest level of initial hCG-rise and the initial hCG-rise in females, having a male partner older than 30 years, was reduced. Moreover, that the risk of preterm birth, birth weight and length at birth was not affected by the selection between competent blastocysts in the In Vitro Fertilization (IVF)-laboratory. However, the selection between competent blastocysts may increase the proportion of boys being born from Assisted Reproduction Technology (ART)-treatments. 

 

Arrangør

Department of Clinical Medicine, Aalborg University

Adresse

Aalborg University in Copenhagen, A.C. Meyers Vænge 15

Mere information

https://aaudk.zoom.us/j/64538643516